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Researchers Develop New Imaging Test to Help Detect Alzheimer's with Greater Accuracy
The scan could help doctors identify tau pathology sooner, and researchers say the findings may improve treatment as therapies work better before major symptoms.
Researchers at UPMC and the University of Pittsburgh School of Medicine developed a new brain imaging test to detect Alzheimer's disease with greater accuracy by identifying tau protein, a biological marker closely tied to future decline.
This research is part of a program that began in 2021 when the University of Pittsburgh was awarded more than $40 million to study tau protein. The study recently appeared on the cover of the worldwide medical journal The Lancet.
Neurologist Dr. Tharick Pascoal noted the new technology allows doctors to clearly identify tau pathology within two or three weeks. "If you find tau pathology in the brain of the patient, very likely these individuals are going to clinically progress, even develop dementia in the coming few months or years," Pascoal said.
Early detection proves vital because emerging therapies work significantly better in individuals without major symptoms, Pascoal stated. The scan enables earlier treatment, potentially delivering better outcomes for patients and their families.
Doctors advise patients to remain vigilant for early signs of Alzheimer's, including memory loss, difficulty finding the right words, and struggling to complete tasks with various steps. Monitoring these symptoms enables timely intervention.