US EditionTriclosan is a pan-uridine 5'-diphospho-glucuronosyltransferase (UGT) and pan-cytochrome P450 (CYP) inhibitor with high selectivity towards CYP2C19
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Triclosan is a pan-uridine 5'-diphospho-glucuronosyltransferase (UGT) and pan-cytochrome P450 (CYP) inhibitor with high selectivity towards CYP2C19
Understanding the clearance pathways of drug candidates and the fraction metabolized (fm) by drug-metabolizing enzymes is one of the major focuses during drug discovery and development process. While selective cytochrome P450 (CYP) inhibitors are widely available, the lack of potent...
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