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Fungal Vaccine Effort Gets $40 Million Federal Boost

The $40 million NIH award supports advancing VXV-01, a dual-antigen vaccine targeting resistant Candida infections in hospitalized and immunocompromised patients to Phase I trials.

Candida species are an increasing cause of invasive fungal disease, particularly in hospitalized and immunocompromised populations. Not only is the arsenal of antifungal medicines and vaccines limited, but emerging resistance—most notably among Candida auris and Candida albicans—contributes to increasing morbidity and mortality rates. There is an urgent need for new therapeutic strategies targeting Candida infections. Now, the Lundquist Institut…

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The Hamilton Spectator broke the news in Hamilton, Canada on Monday, December 15, 2025.
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