US EditionFirst Large-Scale Stem Cell Bank Created to Investigate Alzheimer’s Genetic Risk Factors
- Researchers at ISGlobal and BBRC link partner loss and financial hardship to Alzheimer's biomarkers and brain structure, published in Neurology.
- Driven by evidence that stressful life events harm brain health, prior work showed midlife stress increases Alzheimer’s vulnerability, with exposure varying by gender and education levels.
- Eleni Palpatzis reports MRI and biomarker data showing gender-specific brain changes linked to stress, highlighting differences in gray matter and Alzheimer’s biomarkers.
- Research shows men are more affected by partner loss and unemployment, while women are more vulnerable to financial stress, highlighting the need for gender-specific interventions.
- Future prevention strategies must consider social determinants like gender and education to address disparities in Alzheimer’s risk influenced by stressful life events.
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11 Articles
First large-scale stem cell bank created to investigate Alzheimer’s genetic risk factors
Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10 percent of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong influence on whether or not a person develops AD during their lifetime.
Death of a partner and financial stress linked to increased risk of Alzheimer's disease, differences in brain structure
Stressful life events can negatively impact brain health. Specifically, grief over the loss of a partner has been linked to alterations in biological processes associated with Alzheimer's disease, while unemployment and financial loss have been associated with structural differences in the brain.
New findings in the field of neuroscience suggest that stressful life events can have a detrimental impact on brain health. In particular, research points to a relationship between grief over the loss of a partner and alterations in biological processes linked to Alzheimer's. In parallel, unemployment and economic losses are associated [...] The entry Stress over the death of a partner and economic situation may be risk factors for Alzheimer's a…
The research, published in the journal Neurology, is the result of a collaboration between the Institute of Global Health of Barcelona (ISGlobal), a center promoted by the La Caixa Foundation, and the BarcelonaBeta Brain Research Center (BBRC), center of the Pasqual Maragall Foundation, reports the ISGlobal in a statement this Thursday.It counted with the participation of 1,200 people from the ALFA cohort (ALzheimer's and FAmilies) of the BBRC, …
What Menopause Symptoms Can Tell Us About Alzheimer's Risk
Hot flashes, night sweats, vaginal dryness, urinary tract infections, irregular periods, low libido, trouble sleeping, brain fog, mood swings — and in rare cases,... The post What Menopause Symptoms Can Tell Us About Alzheimer’s Risk appeared first on Being Patient.
A study published Thursday, July 3, 2025, in the journal Neurology found that people living in poverty are more likely to develop Alzheimer's or other forms of dementia, regardless of whether they have a family history of the disease. What did the researchers find? According to the study "Dementia Risk Due to Traumatic Brain Injury in Subtypes of Dementia in the Welsh Population," the medical records of at least 196,000 older people in the Unite…
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