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Targeting Cell Cycle Protein Sensitizes Tumors to Radiotherapy

A study published in Science Immunology has revealed a previously unknown role for a cell cycle protein in helping cancer cells resist the immune response. Experiments in mice show that inhibiting this protein can sensitize tumors to radiotherapy and immunotherapy, offering a promising target to make existing cancer treatments more effective.  The protein in question is known as budding uninhibited by benzimidazoles 1 (BUB1), a kinase located in…
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Inside Precision Medicine broke the news in on Monday, August 11, 2025.
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