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Weight Loss Wipes Out Senescent Fat Cells but Leaves Immune Scars, Study Finds

Summary by News Medical
Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

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It was found that weight loss triggered the decomposition and recycling of fat, a process that could be responsible for reversing the harmful accumulation of lipids in the liver and pancreas.

·Portugal
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World, 11 July 2025 (ATB Digital).— Since 1990, obesity has doubled and by 2022 one in eight people was obese, according to the World Health Organization. Its consequences may be cardiovascular or respiratory diseases, diabetes, cancer and even neurological disorders. For a long time, the problem had simply been reduced to an aesthetic issue, but, in recent years, researchers have deepened the characteristics of this condition with scientific ev…

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A research published in the journal "Nature" explores the phenomenon of "biological resistance", which could explain how people who lose a lot of weight then recover it again.

·Buenos Aires, Argentina
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Observador broke the news in Portugal on Thursday, July 10, 2025.
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