Common Epilepsy Drug Disrupts Early Brain Growth in Human Organoids After 30-Day Exposure

Common epilepsy drug disrupts early brain growth in human organoids after 30-day exposure

It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children. A study conducted by the Karlsruhe Institute of Technology (KIT), the Heidelberg Academy of Sciences and Humanities, the University of Tübingen, and the University Heidelberg using lab-grown tissue models of the human brain gives new insights into the effects this drug has on early brain development. They open new avenues for resea…

Study Reveals How Valproate Affects Early Brain Development: Insights into

In a groundbreaking study that pushes the boundaries of neurodevelopmental research, scientists have employed advanced human brain organoids to unravel the intricate impacts of valproate (VPA), a widely used antiepileptic drug, on early brain development. With epilepsy affecting approximately 40 million individuals globally and valproate being a cornerstone treatment, understanding the drug’s potential neurodevelopmental risks […]