Study reveals a new facet of how pancreatic cancer cells regulate autophagy

Study reveals a new facet of how pancreatic cancer cells regulate autophagy

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.

Pancreatic Cancer Cells Sense ECM to Switch Between Growth and Autophagy

Researchers headed by a team at NYU Langone Health have discovered that a feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy. The researchers say the ability of these cancer cells to adapt quickly and toggle between biological responses makes them more likely to survive and harder to treat. The study revealed a new facet of how pancreatic ductal adenocarcinoma (PDA) cells regula…

Extracellular Matrix Sensing Enables Pancreatic Cancer Cells to Regulate Autophagy Levels

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.