Study: Keto Diet Linked to Small Intestinal Tumors in Mice
Researchers found the effect was driven by dietary fat metabolism, not ketone bodies, and mice on the diet died more quickly.
- MIT researchers published findings in Nature showing a ketogenic diet accelerates small-intestine tumor growth in mice, while suppressing colon tumors in the same animals.
- A 2022 Nature study suggested ketone bodies like BHB suppress colon cancer, leading researchers to expect them to drive these effects. The new study reveals they are "essentially metabolic bystanders."
- Linking tumor growth to fat metabolism, MIT molecular biologist Fangtao Chi found that dietary fat activates proteins called PPARs, causing intestinal stem cells to multiply and increasing cancer risks.
- Commercially available ketone supplements are unlikely to reproduce the diet's risks or benefits, MIT hepatologist Jessica Shay noted, because effects stem from fat metabolism rather than ketone bodies.
- Senior study author Omer Yilmaz says the team is investigating why the same diet produces opposite consequences in adjacent intestinal regions, marking the next phase of their research.
21 Articles
21 Articles
mannheim24.de
op-online.deA new study by MIT researchers shows that the Keto diet is contradictory in terms of tumour growth in the intestine – depending on where exactly. And another insight is interesting for Keto drink fans.
MIT researchers describe a pathway that increases stem cell activity and favors malignant lesions
The ketogenic or keto diet is one of the star food plans to lose weight quickly, beyond drugs such as Ozempic . This regimen induces a rapid loss of weight at the cost of maximizing carbohydrates (less than 50 grams per day). That is, cereals (bread, pasta, rice, flour, corn), potatoes, legumes, alcohol, sugar, sugar, sugar, sweets or honey are avoided. Fruits are also eliminated in the early stages of the diet (only strawberry or blueberry berr…
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