Study: Neanderthal-Inherited Genetic Mutations Decrease Major Muscle Enzyme Activity

Study: Neanderthal-Inherited Genetic Mutations Decrease Major Muscle Enzyme Activity

An AMPD1 variant from Neanderthals reduces enzyme activity by 25% in lab-produced proteins and up to 80% in muscles of genetically modified mice. This variant is present in all sequenced Neanderthals but absent in other species. It entered the modern human gene pool through interbreeding approximately 50,000 years ago, leading to its presence in up [...] The post Study: Neanderthal-Inherited Genetic Mutations Decrease Major Muscle Enzyme Activit…

Study: Genetic Variant Inherited from Neanderthals Reduces Activity of Key Muscle Enzyme

The Neanderthal variant in AMPD1 decreases its enzymatic activity by 25% in lab-produced proteins and by up to 80% in the muscles of genetically engineered mice. The post Study: Genetic Variant Inherited from Neanderthals Reduces Activity of Key Muscle Enzyme appeared first on Sci.News: Breaking Science News.