Statins ‘cut heart risk gap between obese and slim adults’
Researchers found blood pressure and cholesterol levels in adults over 40 with obesity now match peers with normal BMI after wider statin use.
- Research published Wednesday in The Lancet found adults over 40 with obesity now maintain blood pressure and cholesterol levels rivaling peers with normal BMI, analyzing 110 health datasets involving 1 million participants.
- Study co-author Majid Ezzati, a professor of global environmental health at Imperial College London, attributed improvements to increased use of generic blood pressure drugs and statins costing around $100 annually.
- Younger adults under 40 have not experienced these same metabolic benefits and remain at high risk, as Paul Franks, professor of genetic epidemiology at Lund University, warned they lack adequate screening.
- Experts warned that while medication can lower numbers, it may not reverse existing arterial damage like atherosclerosis, and co-author Edward Gregg noted obesity still increases risks for diabetes and cancer.
- Timothy Anderson, primary care physician at the University of Pittsburgh Medical Center, urged earlier risk factor identification in young adults, noting the GLP-1 era has increased younger patient interest in medical management.
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13 Articles
One study shows that those who are very overweight have, in some cases, similar good blood pressure and cholesterol levels to those of normal weight.
Widespread statin use could level heart attack risk between obese and slim adults
Statins, a cholesterol lowering drug taken by about 8 million people in the UK, could be narrowing the heart attack risk between obese adults and those of a healthy weight
Heart risk markers in adults over 40 with obesity increasingly converge with normal BMI levels
Over the last three decades, differences in unhealthy cholesterol levels and blood pressure between older adults with obesity and those with a normal body mass index (BMI) have narrowed or disappeared in several high-income countries, suggests a study published in The Lancet. The authors propose that this trend is due to the greater, and possibly more intensive, use of cholesterol-lowering medication (such as statins) and blood pressure medication in people older than 40 living with obesity in high-income countries.

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