Hormone Therapy Linked to Lower Dementia Risk in Women
Researchers found unemployment was the strongest social risk factor, with nearly 20,000 women followed for 10.8 years.
- Recently, a large-scale study published in Neurology linked unemployment to increased mortality and dementia risk for women with early natural menopause, which affects roughly 6% of women globally.
- Separately, researchers analyzed records from more than 21,000 women to assess whether estrogen-only hormone therapy influences Alzheimer's-related brain changes and dementia diagnoses later in life.
- Participants using estrogen-only therapy showed 35% lower odds of Alzheimer's pathology and 39% lower odds of a clinical dementia diagnosis compared to non-users.
- Lead author Jennifer L. Bruno, PhD, of Stanford Medicine noted findings do not establish causality and do not change current clinical recommendations due to study limitations.
- Dr. Dung Trinh of MemorialCare Medical Group advocated for an individualized, life-course approach to brain health, noting that more research is needed before recommending hormone therapy for dementia prevention.
32 Articles
32 Articles
Women are significantly more affected by Alzheimer's than men. One reason may be the decline in sex hormones in menopause. A certain hormone therapy could protect, a recent study shows.
Estrogen Therapy May Help Protect Against Alzheimer’s Disease, Study Says
—Lucy Lambriex—Getty ImagesAlzheimer’s dementia is generally more prevalent in women than in men, and doctors believe that one reason why is the sudden drop in estrogen after menopause, which can affect the brain. A new study published in Neurology seems to support this theory. Researchers analyzed the health records of more than 5,000 older women with hysterectomies who had died and had an autopsy of their brains. Those who had received estroge…
Dementia: Study links estrogen-only menopausal therapy to lower risk
A study found that people who used estrogen-only menopausal hormonal therapy were less likely to show increased Alzheimer’s disease pathology, and lower chances of memory decline and a dementia diagnosis.
Coverage Details
Bias Distribution
- 53% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
