Human Antibodies Drive Breakthrough in Broad-Spectrum Snake Antivenom
- Tim Friede, bitten by venomous snakes over 200 times mainly on purpose at his Wisconsin home, has developed immunity that scientists are studying.
- Friede acquired immunity by injecting increasingly larger doses of venom from many deadly snakes during nearly 18 years of self-immunization.
- Researchers led by Centivax identified two antibodies in Friede’s blood that neutralize venom from multiple snake species including cobras, mambas, and kraits.
- Dr. Jacob Glanville said the antibody cocktail provided full protection for 13 of 19 deadly snake species tested in mice, with partial protection for others.
- While the findings suggest a path to broad-spectrum antivenom, experts emphasize this early research requires years more before human trials and is not a replacement for medical advice.
116 Articles
116 Articles
Medicine - Hobby researcher administers snake poison - his blood could save lives
The blood of a hobby researcher could soon help against deadly snake bites. For more than 18 years, the US-American has administered more than 850 times small amounts of snake poison until his immune system had produced antibodies against the poison of several snakes. A research team in the US has now developed a drug that protects against the poisons of 13 different types of natters.


‘Super antibodies’ for snake toxins: how a dangerous DIY experiment helped scientists make a new antivenom
Scientists in the United States have created a new snake antivenom using the blood of a man who deliberately built up immunity to snakebites by injecting himself with many different kinds of venom more than 800 times over 18 years. The researchers showed “super antibodies” from the man’s blood prevented toxic damage from neurotoxins found in the venoms of 19 different snake species, including mambas and cobras. The new study may represent a welc…
Tim Friede: The Human Antivenom Experiment | Science-Environment
Tim Friede: The Human Antivenom Experiment Tim Friede, known for intentionally sustaining hundreds of snake bites, is at the center of scientific research aimed at developing a revolutionary antivenom treatment. His fascination with venomous creatures led him to inject himself with small doses of snake venom, gradually building resistance through years of exposure.Friede's unusual approach, though unadvised by medical professionals, mimics the b…
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