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Psilocybin Therapy Offers "Paradigm-Changing Alternative" to Conventional Treatment for Depression, Clinical Trials Show

UNITED STATES, JUN 16 – Over half of cancer patients experienced sustained remission of depression symptoms two years after a single psilocybin dose combined with psychotherapy, indicating durable therapeutic effects.

  • A single dose of psilocybin has been shown to provide lasting relief from depression and anxiety in cancer patients suffering from major depressive disorder, according to results from a clinical trial.
  • Two years post-treatment, 53.6% of patients demonstrated significant depression reduction, with 50% achieving sustained remission.
  • At the two-year follow-up, psilocybin reduced anxiety in 42.9% of patients.
  • These findings suggest that psilocybin-assisted therapy may serve as a potent and safe alternative to conventional antidepressants for cancer patients' emotional challenges.
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Medical Xpress broke the news in Douglas, United Kingdom on Monday, June 16, 2025.
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