Single dose of 5-MeO-DMT alters gene expression in brain and reduces anxiety-like behavior in stressed mice

Single dose of 5-MeO-DMT alters gene expression in brain and reduces anxiety-like behavior in stressed mice

A new study published in Molecular Psychiatry suggests that the fast-acting psychedelic compound 5-MeO-DMT can reduce anxiety-like behavior in stressed mice while altering the expression of genes linked to neural activity in specific brain regions. The research found that a single dose of 5-MeO-DMT modified expression of immediate early genes and affected behavioral responses up to five days later, offering insights into how this compound might …