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Singapore confirms first two locally transmitted mpox cases; authorities say risk to public is low
On Thursday, the Communicable Diseases Agency confirmed Singapore's first two locally transmitted mpox cases in men aged 30 and 34, both infected with the more severe clade 1b variant and in stable condition.
Clade 1b, which is typically more severe than clade 2 infections, first emerged in the Democratic Republic of Congo in 2023 and drove a surge in African countries in 2024.
According to the CDA, the 34-year-old man had recent travel and 'prolonged physical contact' with the 30-year-old patient; both men likely contracted the virus through sexual contact.
The CDA assessed the risk to the general public as low, as transmission typically requires intimate or prolonged physical contact. Investigations and contact tracing are ongoing, with High-risk contacts recommended for vaccination.
Investigations and contact tracing continue as Singapore reported Twenty-three cases in 2025, providing context for these first locally transmitted infections detected this year.