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Serena Williams Tells Oprah Winfrey Why She Initially Thought Weight Loss Shots Were a “Shortcut”

Serena Williams addresses criticism over using weight-loss injectable Zepbound, highlighting health benefits and body positivity during motherhood and aging on The Oprah Podcast.

Summary by E! News
Serena Williams discussed why she ultimately decided to use a GLP-1 medication to lose weight in E! News’ exclusive clip of her conversation with Oprah Winfrey on The Oprah Podcast.

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E! News broke the news in United States on Tuesday, January 13, 2026.
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