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Semaglutide Reduces Murine Blood Pressure through the Vascular Smooth Muscle GLP-1 Receptor
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Semaglutide Reduces Murine Blood Pressure through the Vascular Smooth Muscle GLP-1 Receptor
Investigators showed that GLP-1 receptors (GLP-1Rs) in vascular smooth muscle cells are essential for semaglutide-mediated blood pressure (BP) reduction in mice. In contrast, GLP-1Rs in Tie2+ endothelial or immune cells are not required for semaglutide to lower BP. [JCI Insight] AbstractGraphical Abstract
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