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Seahawks vs. 49ers Prediction, Odds, Time, Spread: NFL Week 18 Saturday Picks by Proven Model

The SportsLine Projection Model has revealed its San Francisco vs. Seattle picks for Week 18 Saturday with NFC's top seed on the line

The SportsLine Projection Model has revealed its San Francisco vs. Seattle picks for Week 18 Saturday with NFC's top seed on the line

4 hours ago·United States

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CBS Sports broke the news in United States 4 hours ago on Wednesday, December 31, 2025.

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SportsLine's model projects a 51-point total and indicates one side of the spread hits in over 50% of simulations for the NFC top seed clash.