See every side of every news story
Published loading...Updated

Clinical Trial Examines Whether Ambroxol Can Slow Dementia in People with Parkinson's

EUROPE, JUN 30 – A 12-month trial with 55 participants showed Ambroxol stabilized psychiatric symptoms and brain damage markers, offering potential brain protection in Parkinson's disease dementia.

  • A 12-month clinical trial conducted in Canada and published today in JAMA Neurology evaluated Ambroxol's effects in a group of 55 individuals diagnosed with dementia associated with Parkinson's disease.
  • Researchers conducted the study because current therapies only address symptoms and do not stop the progression of Parkinson's dementia.
  • The trial randomized participants to daily Ambroxol or placebo and monitored memory, psychiatric symptoms, and a brain damage marker called GFAP.
  • Results showed Ambroxol was safe, well-tolerated, reached therapeutic brain levels, stabilized psychiatric symptoms, and maintained stable GFAP levels unlike placebo.
  • Pasternak and his team plan a follow-up trial later in 2025 focused on cognition, hoping further research confirms Ambroxol’s potential to change Parkinson's dementia's course.
Insights by Ground AI
Does this summary seem wrong?

15 Articles

Think freely.Subscribe and get full access to Ground NewsSubscriptions start at $9.99/yearSubscribe

Bias Distribution

  • 33% of the sources lean Left, 33% of the sources are Center, 33% of the sources lean Right
33% Right

Factuality 

To view factuality data please Upgrade to Premium

Ownership

To view ownership data please Upgrade to Vantage

The London free Press broke the news in London, Canada on Monday, June 30, 2025.
Sources are mostly out of (0)