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Study Uncovers a Neural Brake that Limits Motivation During Unpleasant Situations

Suppressing a brain circuit in macaques increased initiation of unpleasant tasks, revealing a 'motivation brake' that may explain apathy in depression and schizophrenia.

Summary by News Medical
Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

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The first step in unpleasant tasks is particularly difficult. A research team has determined in macaques which brain areas have a braking effect

·Vienna, Austria
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Nature broke the news in London, United Kingdom on Friday, January 9, 2026.
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