Rarely Studied RNA Linked to Triple-Negative Breast Cancer

Rarely studied RNA linked to triple-negative breast cancer

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable.

JCI A triple-punch approach: methionine restriction enhances combination inhibitors in brain metastatic triple-negative breast cancer

Triple-negative breast cancer (TNBC), the most aggressive subtype of breast cancer, presents a clinical challenge in developing effective treatment options. In this issue of the JCI, Zeng et al. demonstrate a provocative and promising therapeutic strategy for TNBC by leveraging the metabolic vulnerabilities presented by methylthioadenosine phosphorylase (MTAP) deletion to genotoxic stress inducers, such as poly (ADP-ribose) polymerase inhibitors…

MRI predicts treatment response for triple-negative breast cancer

Post-treatment MRI can accurately predict treatment response for early triple-negative breast cancer, according to recent research.

Scientists Discover New Connection to Triple-Negative Breast Cancer

Breast cancer stands as one of the foremost health challenges impacting women globally, and despite significant advances in diagnosis and treatment, certain aggressive subtypes continue to evade effective therapeutic intervention. Among these, triple-negative breast cancer (TNBC) remains particularly formidable. Representing approximately 10 to 15 percent of breast cancer diagnoses, TNBC disproportionately affects younger women and African Ameri…

A new "link" to triple-negative breast cancer

COLD SPRING HARBOR, N.Y., June 30, 2025 /PRNewswire/ -- Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable. The exception is…

A new “link” to triple-negative breast cancer | Cold Spring Harbor Laboratory

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it’s also one of the most curable. The exception is a particularly aggressive variant known as triple-negative breast cancer (TNBC). It accounts for 10 to 15 percent of all breast cancer cases. It disproportionately affects younger and African American women. No effective therapies exist. A new discovery by Cold Spring Har…