Retinal organoid study identifies pathways and compounds to protect cone cells

Retinal organoid study identifies pathways and compounds to protect cone cells

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

Scientists Discover How to Stop Vision Loss Before It Starts

Scientists have identified molecules that can protect the eye’s cone cells from degeneration, a major cause of vision loss. The discovery points to new drug targets—and even uncovers compounds that may be harmful. Researchers led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB), along with an international team, have uncovered [...]

New Compounds Identified to Save Human Color Vision

Researchers screened 2,700 compounds on 20,000 human retinal organoids to find a way to stop cone cell death. They discovered that inhibiting casein kinase 1 can protect central vision from macular degeneration.