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Psilocybin impacts immunity and behavior differently depending on diet and exercise context

Monash researchers found psilocybin increased interleukin-6 in exercising mice but did not affect social behaviors in anorexia models, indicating context-dependent effects.

Summary by PsyPost
A new study published in the journal Psychedelics reveals that the environment and physiological state of an animal profoundly influence the effects of psilocybin. Researchers found that while the drug altered immune markers in mice that exercised, it did not modify social behaviors in mice modeling anorexia nervosa. These findings suggest that the therapeutic potential of psychedelics may depend heavily on the biological context in which they a…

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PsyPost broke the news in on Wednesday, February 4, 2026.
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