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Protocol enables ERT after Pompe disease treatment reaction

Summary by Pompe Disease News
A desensitization protocol allowed doctors to successfully treat an infant with classic infantile-onset Pompe disease (IOPD) who developed an allergic reaction to Myozyme (alglucosidase alfa), according to a report. The protocol, which was also used when the patient switched to Nexviadyme (avalglucosidase alfa), involved delivering the Pompe disease treatment at a gradually increasing dose together with medication to reduce allergic and inflamma…
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Pompe Disease News broke the news in on Thursday, April 10, 2025.
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