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PLSCR1 Identified as Novel NEDD4-2 Ubiquitination Target

Summary by BIOENGINEER.ORG
In a breakthrough that promises to deepen our understanding of cellular regulatory mechanisms, researchers have identified phospholipid scramblase 1 (PLSCR1) as a previously unknown substrate of ubiquitination mediated by the E3 ubiquitin ligase NEDD4-2, also known as NEDD4L. This revelation sheds new light on the complex pathways governing membrane dynamics and cellular homeostasis, with implications […]
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BIOENGINEER.ORG broke the news in on Wednesday, August 20, 2025.
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