One Dose of Experimental Antibody Kept HIV-Like Virus in Remission For 4 Years in a Monkey
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5 Articles
One Dose of Experimental Antibody Kept HIV-Like Virus in Remission For 4 Years in a Monkey
"May be a surprisingly effective route to HIV cure."ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
Eradicating dormant viral reservoirs represents the Grail of modern infectious research. The human immunodeficiency virus has in fact the stealth ability to hide at the very heart of immune cells, thus escaping conventional therapies. Recently, scientists have taken a decisive step by testing an innovative molecule on young primates. ... Read more The article A scientific discovery maintains a simian virus in remission for four years has appeare…
Scientists have developed an experimental antibody that left a baby monkey infected with an HIV-like virus undetectable in its blood for four years after treatment was discontinued. The research suggests that this approach, which targets the cells where the virus hides in the body, could be a new option in HIV treatment, although its effectiveness in humans remains unclear.
HIV can go dormant without disappearing from the body. Hidden in immune cells, it can survive treatment and start multiplying again
HIV Remission in Monkeys Study
A single dose of an experimental antibody kept a virus similar to HIV in remission for four years in a monkey. What Happened in the Study Researchers infected 20 newborn rhesus macaques with simian immunodeficiency virus (SIV), a relative of HIV. The animals were split into three groups. One got only antiviral drugs. A second got drugs plus a single dose of a CCR5/CD3 antibody. A third got a different antibody targeting CD4. Antiviral treatment …
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