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Tourmaline Bio Enters Into Agreement to Be Acquired by Novartis AG

Novartis will acquire Tourmaline Bio for $1.4 billion to gain pacibekitug, a Phase 3 ready anti-IL-6 therapy targeting systemic inflammation in cardiovascular disease.

  • In Basel on September 9, 2025, Novartis AG said it will acquire Tourmaline Bio, Inc. for $48.00 per share, valuing the company at approximately $1.4 billion.
  • Novartis cited clinical readiness and strategic fit, with Pacibekitug previously studied in approximately 450 participants, supporting its potential in cardiovascular indications.
  • Study results and product properties demonstrate that pacibekitug, studied in approximately 450 participants, has a long half-life enabling once-quarterly dosing, with Phase 2 TRANQUILITY study results released May 20, 2025 showing median hs-CRP reductions of 85%.
  • Both companies' Boards unanimously approved the deal, and Novartis will commence a tender offer via a Novartis indirect wholly owned subsidiary to buy shares at $48.00 each, with completion expected in the fourth quarter of 2025.
  • Novartis framed the deal as expanding its cardiovascular pipeline and reaches more than 250 million people worldwide; it noted forward-looking disclaimers with no guarantee of clinical success.
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An acquired drug will complete the current portfolio of medicines for cardiovascular diseases of Novartis

·Milan, Italy
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Globe Newswire broke the news in on Tuesday, September 9, 2025.
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