US EditionNo link between Tylenol use in pregnancy and autism or ADHD, new study finds
A review of 43 studies found no significant autism, ADHD, or intellectual disability risk from acetaminophen during pregnancy, supporting medical guidelines for its safe use.
- Published Friday, a major meta-analysis pooling about 60 studies found that acetaminophen taken as directed in pregnancy is not linked to autism, ADHD or intellectual disability.
- Earlier studies showed mixed results, leaving pregnant people unsure about acetaminophen safety as study authors noted symptoms like fever, infection, pain and inflammation may confound links to fetal brain development.
- Focusing on sibling-comparison designs, the review emphasized studies comparing siblings with and without prenatal acetaminophen exposure and included follow-up longer than five years.
- Study authors and clinicians said pregnant women should feel reassured that acetaminophen remains the recommended first-line option for pain or fever in pregnancy when used as directed, and ACOG advises the lowest effective dose for the shortest time with care for persistent or high fever.
- Voices outside the study cautioned or criticized, including an HHS official who said it "does not resolve an important public health question; it sidesteps it," while President Donald Trump and the FDA debated acetaminophen's safety and Kenvue defended Tylenol.
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184 Articles
Paracetamol in pregnancy not linked to Autism or ADHD: Study
Adelaide: If you’ve been pregnant in the past few months, you may have faced a dilemma. You wake up with a fever, a pounding headache or back pain, and then pause. Is it safe to take paracetamol? That hesitation isn’t surprising. In September last year, the United States government sowed widespread doubt and anxiety by linking paracetamol use in pregnancy to autism and attention-deficit hyperactivity (ADHD). But now a major new international stu…
The use of paracetamol during pregnancy does not increase the risk of autism, ADHD or mental disability. This confirms a recent review and thus refutes statements by US President Trump.
Donald Trump bested by his one unbeatable enemy
When Robert F. Kennedy Jr. announced that the Donald Trump administration would reopen investigations into the causes of autism, he promised it would be an “unbiased, depoliticized, gold standard scientific research and academic freedom.” Eventually, they declared that Tylenol during pregnancy is a huge determinant in which infants get autism — now a group of researchers have released possibly the most thorough analysis on the topic yet. When Tr…
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