US EditionNew study directly links higher BMI to increased risk of vascular dementia
A Mendelian randomization study links high BMI and blood pressure as direct causes of vascular dementia, with blood pressure mediating up to 25% of the risk, researchers say.
- Published today, the research found high BMI and high blood pressure are direct causes of vascular-related dementia in The Journal of Clinical Endocrinology & Metabolism.
- To resolve causation questions, researchers used Mendelian randomization to reduce confounding, as previous observational studies linked midlife obesity to dementia but could not establish causation.
- Using genetic and health records from Copenhagen and the U.K., the team found that a 4.5-point increase in body mass index raised vascular dementia risk across all BMIs.
- Public-Health measures to lower BMI and blood pressure could prevent many vascular-related dementia cases, highlighting the importance of population-level prevention, researchers found.
- An important unanswered question is whether early intervention with weight-loss treatments may protect against dementia, as weight-loss medication recently tested in early phases of Alzheimer's disease showed no benefit, while dementia currently affects 50 million individuals worldwide.
42 Articles
42 Articles
This Surprising Factor Could Increase Your Dementia Risk by 31%, According to New Research
Here's how your social life could affect your dementia risk.Reviewed by Dietitian Sarah Pflugradt, Ph.D., RDN, CSCSGetty Images. EatingWell design.Key PointsResearch suggests that loneliness can increase dementia risk by 31%. Loneliness may lead to unhealthy behaviors, such as inactivity and isolation. Reach out to family or friends, join a group or volunteer to decrease loneliness. Dementia and brain disorders are getting a lot of attention the…
(Seoul = Yonhap News) Reporter Lee Ju-young = People with a high body mass index (BMI) due to obesity may have a higher risk of dementia, and in the process, hypertension caused by obesity...
Increased BMI, blood pressure may raise odds for vascular-related dementia
Adults with higher BMI or increased blood pressure may be more likely to develop vascular-related dementia, researchers reported in The Journal of Clinical Endocrinology & Metabolism. “Our findings show that overweight and high blood pressure are direct causes of increased dementia risk — that makes them highly actionable targets for dementia prevention at the population level,” Ruth
High BMI linked to vascular dementia risk
High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular + unspecified dementia), according to new research from the University of Bristol and University Hospital of Copenhagen (Rigshospitalet and Herlev-Gentofte hospital).
Coverage Details
Bias Distribution
- 56% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
