Published • loading... • Updated
Researchers Identify New Depression Subtype Linked to the Body Clock
The subtype affects about one-quarter of participants and may not respond to standard antidepressants or cognitive behavioral therapy, researchers said.
- On Wednesday, University of Sydney researchers identified a 'circadian depression' subtype in about one in four patients within a study of 11,380 Australians, published in The British Journal of Psychiatry.
- Disrupted body clocks drive this subtype, with patients reporting 'night owl' habits, social jet lag, and seasonal mood changes, according to Professor Ian Hickie, co-director of the Brain and Mind Centre.
- Participants with this subtype, which affected 2,604 people, developed symptoms earlier—around age 19—and face a higher genetic risk for ADHD and bipolar disorder than others in the cohort.
- Lead researcher Emiliana Tonini suggested targeted treatments such as melatonin or light therapy could better assist these individuals, as common SSRIs may be less effective for this subtype.
- Researchers caution that further clinical trials are needed to validate these findings across broader populations before shifting standard diagnostic practices, as circadian depression remains a proposed subtype.
Insights by Ground AI
12 Articles
12 Articles
Researchers Identify New 'Circadian' Subtype of Depression Affecting 1 in 4 Patients
Many people with depression don't respond to existing treatments, and scientists think it might be because of the many different routes people can take to arrive at the same depressive symptoms.
·Canberra, Australia
Read Full Article
Proposed depression subtype involves waking up tired or being a night owl
A new study suggests one in four people with severe, recurrent or persistent depression have a proposed subset called "circadian depression", where people often report waking up very tired and being a "night owl".
·Ultimo, Australia
Read Full Article
According to a study with clinical and genetic data from more than 10,000 Australians, it accounts for almost a quarter of diagnoses in people with severe, recurrent or persistent depression.
·Madrid, Spain
Read Full ArticleCoverage Details
Total News Sources12
Leaning Left4Leaning Right3Center5Last UpdatedBias Distribution42% Center
Bias Distribution
- 42% of the sources are Center
42% Center
L 33%
C 42%
R 25%
Factuality
To view factuality data please Upgrade to Premium
