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New members of the CDKL family of genes linked to neurodevelopmental disorders

Summary by Science Daily
Researchers have deepened our understanding of two of the five members of the CDKL family of genes, CDKL2 and CDKL1. They show that variants in these genes can lead to neurodevelopmental conditions, including epilepsy, and propose a mechanism by which the defective variants may cause the neurological symptoms in affected individuals.

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New members of the CDKL family of genes linked to neurodevelopmental disorders

Researchers have deepened our understanding of two of the five members of the CDKL family of genes, CDKL2 and CDKL1. They show that variants in these genes can lead to neurodevelopmental conditions, including epilepsy, and propose a mechanism by which the defective variants may cause the neurological symptoms in affected individuals.

·United States
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Baylor College of MedicineBaylor College of Medicine

New CDKL genes linked to neurodevelopmental disorders

CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures. However, the role the...

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Medical Xpress broke the news in on Friday, March 14, 2025.
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