New Clue in Alzheimer's Research: Immune System Unable to Reach the Brain.
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Researchers have discovered an unexpected immune mechanism outside the brain that contributes to damage in Alzheimer's disease. Blocking this process largely protected the experimental mice from neurodegeneration.
Immune cells activated in lymph nodes could promote brain degeneration, according to research in mice.
Notable findings in Alzheimer's research suggest that bone marrow may play a role in the production of immune cells involved in fighting the disease. Researchers determined that monocyte production is disrupted in Alzheimer's, leading to accelerated aging signs in the blood system.
A new study suggests that bone marrow damage triggered by Alzheimer's may explain why the body's immune system fails to restore brain health in this neurodegenerative disease. Decades of research on Alzheimer's disease have focused on the role played by misfolded proteins in the brain, including amyloid-beta plaques and knotted tau proteins. However, some of the most significant damage associated with this disease may occur far from the brain, i…
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