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Neanderthal males and human females had babies together, ancient DNA reveals

Genetic analysis shows Neanderthal DNA averages 1-2% in modern non-African humans and suggests male Neanderthals predominantly mated with female Homo sapiens.

  • On Feb. 26, the journal Science published a University of Pennsylvania study finding interbreeding was mostly between male Neanderthals and female anatomically modern humans.
  • Before this study, scientists suggested natural selection or incompatibility hypotheses to explain the 'Neanderthal deserts' in the human X chromosome.
  • Comparing Neanderthal and human genomes revealed Neanderthal X chromosomes carry 62% more human DNA than other chromosomes, a mirror pattern supporting mating behavior.
  • The study suggests this pattern helps explain present‑day Neanderthal ancestry, revealing why modern humans have low, uneven Neanderthal DNA affecting circadian rhythms, immune system function and pain.
  • The authors caution that alternatives remain plausible as the study cannot rule out lower survival of offspring from human males and Neanderthal females, and research is limited by a handful of high-quality Neanderthal genomes and modelling and simulations.
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44 Articles

KHQ Right NowKHQ Right Now
+2 Reposted by 2 other sources
Center

The sex lives of Neanderthal males - and human females

Dating out of your league? New research says it's a tale as old as time.

·Spokane, United States
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Daily JournalDaily Journal
+4 Reposted by 4 other sources
Center

Ancient coupling may have happened more between human females and Neanderthal males

Ancient linkups may have happened more frequently between female humans and male Neanderthals, according to an new genetic analysis. Scientists know that Neanderthals and humans mated because there is a small percentage of Neanderthal DNA in most modern humans. But…

·Cherokee County, United States
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Lean Left

Archaeogenetics: Around 50,000 years ago, there was regular sexual contact between Neanderthals and Homo sapiens. Now it turns out that this was mainly about…

·Netherlands (Kingdom of the)
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Nature broke the news in United Kingdom on Thursday, February 26, 2026.
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