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Naloxone's molecular blueprint holds the key to next-generation opioid
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1 Articles
Naloxone's molecular blueprint holds the key to next-generation opioid
A comprehensive review of naloxone's chemistry, receptor pharmacology and clinical pharmacokinetics explains why the lifesaving opioid antagonist acts so quickly yet wears off so soon, and how its finely tuned molecular structure could guide the design of longer-acting next-generation overdose antidotes.
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