US EditionmRNA covid vaccines spark immune response that may aid cancer survival: Study
- On October 19, 2025, investigators at The University of Texas MD Anderson Cancer Center reported that patients who received mRNA COVID vaccines within 100 days of starting immunotherapy were twice as likely to be alive after three years.
- Researchers at The University of Texas MD Anderson Cancer Center traced the effect to mRNA vaccines acting as an immune alarm, supported by Grippin and Sayour's lab finding non-specific mRNA vaccines train immune systems to attack cancer.
- In a study of over 1,000 patients treated from 2019 to 2023, 180 lung cancer patients had median survival of 37 months versus 20 months in 704 unvaccinated patients, and 43 vaccinated melanoma patients had not yet reached median survival compared to 167 unvaccinated.
- Investigators found the biggest benefits in immunologically "cold" tumors, with survival gains most pronounced and immune activation plus higher PD-L1 suggesting sensitization to checkpoint inhibitors.
- Despite the promise, researchers and independent experts warn the research is early and retrospective, requiring validation in randomized clinical trials amid recent US cuts to mRNA vaccine development funding.
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28 Articles
New studies suggest that mRNA vaccines developed for Covid-19 may have an unexpected effect: strengthen the immune system to improve the results of oncological treatments such as immunotherapy. The next vaccine...
mRNA Covid Vaccines May Supercharge Cancer Treatments, Doubling Survival Rates in New Study
New research suggests mRNA Covid-19 vaccines may help cancer patients live nearly twice as long by boosting the power of immunotherapy. Scientists say this unexpected link could transform how doctors fight cancer.
Covid vaccine shows promise against cancer
A vaccine originally designed to protect against Covid-19 has shown unexpected promise in helping the immune system fight cancer, according to new research unveiled at the European Society for Medical Oncology (ESMO) conference in Berlin. Scientists have discovered that the mRNA technology used in Covid vaccines may enhance the effectiveness of certain cancer immunotherapies… Source
Science Daily
UpstractCancer patients who got a COVID vaccine lived much longer
A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from the University of Florida and MD Anderson Cancer Center discovered that the vaccine’s immune-activating properties may boost cancer-fighting responses, acting like a nonspecific “flare” that reawakens the immune system.
In addition to protecting against the virus that caused a global pandemic, they could stimulate the immune system to fight tumors during cancer treatment. This is reflected in the results of a research presented this Sunday in Berlin at a conference of the European Society of Medical Oncology. As the NBC News medium reveals, the research is still at a very preliminary stage and has not yet been tested in a phase three clinical trial, but the tru…
Observador
MRNA vaccines, such as those used against covid-19, have the ability to stimulate immune response against cancer, allowing patients to live longer, reveals research.
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