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Moderna receives $54.3M investment for bird flu vaccine, covering axed federal mRNA contracts

Moderna receives $54 million to advance its bird flu vaccine to pivotal trials after a $760 million federal contract was canceled amid pandemic preparedness concerns.

  • After the Department of Health and Human Services canceled a $760 million contract in May, Moderna secured $54 million to develop an mRNA H5 bird flu vaccine for pivotal trials.
  • Public health officials say the avian H5 strain poses a significant pandemic risk, and the World Health Organization said studied bird flu vaccines reduce future pandemic likelihood while mRNA technology targets the 100-day goal.
  • CEPI will bankroll a phase‑three trial for Moderna's H5 vaccine, which Moderna pledged to reserve 20% of production for low‑income countries at affordable prices.
  • The trial is scheduled to start early next year, underscoring urgency because in a pandemic 'every day counts,' while some critics called the cancellation shortsighted, and HHS promised safe, effective vaccines.
  • Dr. Richard Hatchett, CEO of CEPI, said pandemic influenza is a top threat to global health security, while mRNA technology aims to cut response times drastically for vaccine designers.
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KBZK broke the news in on Thursday, December 18, 2025.
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