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Mitochondrial Signaling Drives High-Altitude Adaptation Mechanism
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Mitochondrial Signaling Drives High-Altitude Adaptation Mechanism
In a groundbreaking study published in 2026 in the journal Cell Death Discovery, researchers have uncovered a molecular mechanism crucial to the remarkable high-altitude adaptation observed in Tibetan populations. This work delineates how mitochondrial retrograde signaling orchestrates a cellular response involving HIF-1α and the mitophagy mediators BNIP3 and NIX, providing new insights into the intricate […]
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