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Mitochondrial Dysfunction in Parkinson's Disease is Complicated
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Mitochondrial Dysfunction in Parkinson's Disease is Complicated
Like many age-related conditions, Parkinson's disease is associated with uncommon mutations and genetic variants that increase its likelihood, severity, and pace of progression. PINK1 is a protein involved in identifying damaged mitochondria to be broken down by the quality control mechanisms of autophagy. Loss of effective PINK1 function clearly accelerates mitochondrial dysfunction and increases cell death in neurons placed under the stress in…
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