Methotrexate Found to Be Effective Alternative to Prednisone for Pulmonary Sarcoidosis

Methotrexate found to be effective alternative to prednisone for pulmonary sarcoidosis

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects.

Methotrexate Proves Its Mettle as First-Line Therapy for Pulmonary Sarcoidosis

(MedPage Today) -- For initial treatment of symptomatic pulmonary sarcoidosis, methotrexate appeared to work as well as prednisone over 24 weeks, the randomized PREDMETH trial showed. Mean change from baseline in the percentage of predicted forced...

Methotrexate as effective as prednisone in pulmonary sarcoidosis, research finds

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research, published at the ATS 2025 International Conference and in the American Journal of Respiratory and Critical Care Medicine, finds that methotrexate provides a comparable alternative.

Fabricated Stone Workers May Face Risk of New Lung Disease: Silicosarcoidosis

Researchers hope the new term will help doctors identify and treat the condition, which occurs when patients suffer from both silicosis and sarcoidosis. Amid rising concern over silicosis, an incurable lung disease linked to silica dust exposure in the fabricated stone industry, new research suggests the condition may be more complex than previously believed.…

Methotrexate Effective as Alternative to Prednisone for Pulmonary Sarcoidosis

These data, presented at ATS 2025, highlight the efficacy results of methotrexate when compared to prednisone for pulmonary sarcoidosis.

Methotrexate as Effective as Prednisone in Pulmonary Sarcoidosis

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International Conference finds that methotrexate provides a comparable alternative.