Skip to main content
Holiday Sale — Get 40% off Vantage for yourself or as a gift
Published loading...Updated

Major Study Finds Hormone Therapy Doesn’t Increase Dementia Risk

A systematic review of over 1 million participants found no link between menopause hormone therapy and dementia risk, supporting current clinical guidance, WHO said.

  • A WHO-commissioned review published in The Lancet Healthy Longevity by University College London researchers found no significant link between menopause hormone therapy and dementia risk.
  • Amid conflicting studies and past warnings, researchers reviewed menopause hormone therapy as the FDA removed black box warnings, addressing uncertainty for clinicians and women considering HRT.
  • The researchers pooled evidence from one randomized controlled trial and nine observational studies totalling 1,016,055 participants, including patients with mild cognitive impairment, women with early menopause and premature ovarian insufficiency.
  • The review reinforces current clinical guidance that clinicians and prescribers should base HRT prescriptions on benefits and risks, not dementia prevention, while calling for more research on women from ethnic minority backgrounds or those with early menopause or mild cognitive impairment .
  • The review highlights tensions between recent policy moves and available data as the U.S. Food and Drug Administration suggested menopause hormone therapy might reduce Alzheimer's risk, yet scarce randomized controlled trials and low-certainty evidence leave this claim unsupported.
Insights by Ground AI

42 Articles

ABC FOX MontanaABC FOX Montana
+32 Reposted by 32 other sources
Center

Major study finds hormone therapy doesn’t increase dementia risk

The findings show no evidence to suggest that hormone replacement therapy (HRT) either increases or decreases dementia risk in post-menopausal women.

·Missoula, United States
Read Full Article
The IndependentThe Independent
Reposted by
The Independent (US)The Independent (US)
Lean Left

New study reveals effects of HRT on dementia risk

Research has been done to look into potential links between HRT and the risk of dementia

·London, United Kingdom
Read Full Article
Think freely.Subscribe and get full access to Ground NewsSubscriptions start at $9.99/yearSubscribe

Bias Distribution

  • 50% of the sources are Center
50% Center

Factuality Info Icon

To view factuality data please Upgrade to Premium

Ownership

Info Icon

To view ownership data please Upgrade to Vantage

udgtv broke the news in on Monday, December 22, 2025.
Too Big Arrow Icon
Sources are mostly out of (0)

Similar News Topics

News
Feed Dots Icon
For You
Search Icon
Search
Blindspot LogoBlindspotLocal