Major Study Finds Hormone Therapy Doesn’t Increase Dementia Risk
A systematic review of over 1 million participants found no link between menopause hormone therapy and dementia risk, supporting current clinical guidance, WHO said.
- A WHO-commissioned review published in The Lancet Healthy Longevity by University College London researchers found no significant link between menopause hormone therapy and dementia risk.
- Amid conflicting studies and past warnings, researchers reviewed menopause hormone therapy as the FDA removed black box warnings, addressing uncertainty for clinicians and women considering HRT.
- The researchers pooled evidence from one randomized controlled trial and nine observational studies totalling 1,016,055 participants, including patients with mild cognitive impairment, women with early menopause and premature ovarian insufficiency.
- The review reinforces current clinical guidance that clinicians and prescribers should base HRT prescriptions on benefits and risks, not dementia prevention, while calling for more research on women from ethnic minority backgrounds or those with early menopause or mild cognitive impairment .
- The review highlights tensions between recent policy moves and available data as the U.S. Food and Drug Administration suggested menopause hormone therapy might reduce Alzheimer's risk, yet scarce randomized controlled trials and low-certainty evidence leave this claim unsupported.
42 Articles
42 Articles
Major study finds hormone therapy doesn’t increase dementia risk
The findings show no evidence to suggest that hormone replacement therapy (HRT) either increases or decreases dementia risk in post-menopausal women.
Menopause Hormone Therapy And Brain Health: What Research On 1 Million Women Tells Us
For decades, women facing menopause have received conflicting advice about hormone therapy and brain health. The post Menopause Hormone Therapy And Brain Health: What Research On 1 Million Women Tells Us appeared first on Study Finds.
Menopause hormone therapy not linked to dementia risk in women
A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.
New study reveals effects of HRT on dementia risk
Research has been done to look into potential links between HRT and the risk of dementia
Hormone therapy does not affect dementia risk in older women, study finds
A new large study has found that hormone therapy used during menopause does not increase or decrease the risk of dementia in women. This research, led by University College London (UCL) and requested by the World Health Organization (WHO), helps clear up years of confusion about this topic. The findings were published in The Lancet […] The post Hormone therapy does not affect dementia risk in older women, study finds appeared first on Knowridge …
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