US EditionMen in their 50s may be aging faster due to toxic ‘forever chemicals’
Exposure to PFNA and PFOSA is linked to faster biological aging in men aged 50 to 64, affecting epigenetic markers without proving causation, researchers said.
- On Thursday, the study published in Frontiers in Aging found higher perfluorononanoic acid and perfluorooctanesulfonamide levels strongly predicted faster epigenetic aging in men aged 50–64 using NHANES blood data from 326 participants.
- Decades of use and ubiquity prompted researchers to study PFAS, persistent 'forever chemicals' used since the 1950s in consumer products and found in 98% of Americans’ blood, per the National Academies of Sciences, Engineering, and Medicine.
- Researchers measured 11 types of PFAS in blood, assessed the DNA methylome, and applied a dozen epigenetic 'clocks' to estimate biological aging.
- Authors and external scientists cautioned that the study shows associations, not proof of causation, with Li urging calm and recommending certified water filters while noting regulatory action and environmental cleanup are crucial.
- The American Chemistry Council described the study as 'exploratory' and noted it used a small, older sample, amid ongoing international efforts like the Stockholm Convention on Persistent Organic Pollutants.
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Middle-aged men most vulnerable to aging effects of new PFAS
Per- and polyfluoroalkyl substances (PFAS) – 'forever chemicals' in common parlance – are a class of thousands of synthetic chemicals often used in non-stick coatings, water-resistant fabrics, fire-fighting foams, food packages, cleaning products, and plastics.
PFAS pollution is increasingly being detected in water, soil and tissues of organisms, while some of them have been linked to human cancers, obesity, infertility and hormonal disruptions.
Forever Chemicals Linked to Faster Aging in Middle-Aged Men, Study Finds
A new study shows that exposure to two specific 'forever chemicals' may accelerate biological aging, especially in middle-aged men. These chemicals – PFNA (perfluorononanoic acid) and PFOSA (perfluorooctanesulfonamide) – are just two of the thousands of 'forever chemicals', or to use the more technical term, PFAS (per- and polyfluoroalkyl substances). Used widely since the 1940s and 1950s, PFAS are found in raincoats, upholstery, non-stick pans,…
Toxic chemicals found in certain plastics appear to accelerate the aging of men in their fifties and early sixties compared to women of the same age.
The so-called "eternal chemicals" PFAS appear to be accelerating biological aging in men aged 50 to 65, according to a new study published in the scientific journal Frontiers... The "eternal chemicals" may be accelerating aging in men aged 50 to 65 - ΘΑΦΤΕΜΟΠΟΡΙΚΙ
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