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Mature Intestinal Cells Revert to Stem-Like State to Sustain Colorectal Cancer
Summary by Inside Precision Medicine
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Mature Intestinal Cells Revert to Stem-Like State to Sustain Colorectal Cancer
Researchers at the Stevens Institute of Technology have identified a mechanism that helps explain how colorectal cancer (CRC) develops, persists, and resists treatment. The research, published in the journal Cell Death & Disease, shows that mature intestinal cells that revert to a stem cell-like state can sustain tumor growth more effectively than mutated intestinal stem cells, a finding that could inform new drug development strategies focused …
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