Major cause of inflammatory bowel disease found
- Existing drugs could potentially treat a newly discovered cause of inflammatory bowel disease by targeting a specific part of DNA in immune cells.
- Researchers from the Francis Crick Institute, UCL, and Imperial College London found that these medications reduced inflammation in both immune cells and gut samples from IBD patients.
- No specific drugs currently exist to block this newly discovered DNA activity in immune cells.
22 Articles
22 Articles
'Breakthrough' cause of IBD found – with hopes of treatment
Inflammatory bowel disease affects around half a million people in the UK (Picture: Getty) A major cause of inflammatory bowel disease (IBD) has been discovered, and could be treated with existing drugs. Researchers have hailed the breakthrough as a ‘massive step forwards’ after finding a pattern in our DNA which is present in 95% of people with the disease. IBD is an umbrella term for diseases like Crohn’s disease and ulcerative colitis, whic…
Scientists have discovered a cause of inflammatory bowel disease. They said it's a 'holy grail' discovery that could transform treatments.
Getty Images; Chelsea Jia Feng/BIResearchers used genetic editing to uncover a pathway behind diseases like inflammatory bowel disorder. They say existing drugs could be used to interrupt the inflammation process and help treat patients. Understanding the role of "gene deserts" may offer insight for treating other autoimmune conditions.Scientists have reported a major breakthrough in our understanding of inflammatory bowel disorder. It could lea…

Major cause of inflammatory bowel disease discovered
Researchers have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs.
Scientists discover major cause of inflammatory bowel disease
A team of researchers at the Francis Crick Institute have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs.
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