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Magnetite-Silica Core-Shell Nanoparticles for Anticancer Drug-Mediated Chemo-Hyperthermia: A Box-Behnken Design Approach to Triple-Negative Breast Cancer Therapy

Abstract Triple negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes that is characterized by the lack of clinical targets and the resistance of conventional chemotherapy. We have developed cyclophosphamide loaded magnetic mesoporous nanoparticles (CYP-MMNPs) and optimized the formulation systematically by Box – Behnken Design (BBD) coupled with Response Surface Methodology […] Der Beitrag Magnetite-Silica Core-Shel…
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Pharma Excipients broke the news on Sunday, September 13, 2026.
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