Living drugs that reprogram patients’ immune cells show early promise against hard-to-treat brain tumors

Living drugs that reprogram patients’ immune cells show early promise against hard-to-treat brain tumors

By Brenda Goodman, CNN (CNN) — For decades, a diagnosis of glioblastoma – an aggressive, hard-to-treat cancer in the brain – has been a death sentence for patients. Only 3% to 5% of people who are diagnosed with this type of brain tumor will be alive three years later. On average, patients live about 14 months after diagnosis. Now, an experimental therapy that reprograms a person’s own immune cells to attack these tumors is showing some exciting…

Living drugs that reprogram patients’ immune cells show early promise against hard-to-treat brain tumors

(CNN) — For decades, a diagnosis of glioblastoma – an aggressive, hard-to-treat cancer in the brain – has been a death sentence for patients.

A new strategy to attack aggressive brain cancer shrank tumors in two early tests

By LAURAN NEERGAARD AP Medical Writer WASHINGTON (AP) — Researchers revved up immune cells that shrank an extremely aggressive type of brain tumor when tested in a handful of patients. The experiments are just first steps but they signal a new strategy to fight hard-to-treat glioblastoma. It’s a twist on the CAR-T therapy already used to treat leukemia, by modifying patients’ own disease-fighting T cells to be better cancer hunters. Now Massachu…

A new strategy to attack aggressive brain cancer shrank tumors in two early tests - Seymour Tribune

WASHINGTON (AP) — A new strategy to fight an extremely aggressive type of brain tumor showed promise in a pair of experiments with a handful of patients. Scientists took patients’ own immune cells and turned them into “living drugs” able to recognize and attack glioblastoma. In the first-step tests, those cells shrank tumors at least […]

Living drugs that reprogram patients’ immune cells show early promise against hard-to-treat brain tumors

Three studies published within the past week have reported dramatic results with a therapy called CAR-T delivered directly to the brain. In some cases, tumors have seemingly melted away on brain scans by the next day.