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Sen. Bill Cassidy’s defeat shows the price of dissent in Trump’s Republican Party

Trump-backed candidates advanced to a runoff as Cassidy finished third, making him the first Republican Senate incumbent to lose renomination since 2012.

  • On Saturday, Louisiana Sen. Bill Cassidy lost his GOP renomination bid after finishing third in the primary, while Rep. Julia Letlow and State Treasurer John Fleming advanced to the runoff.
  • Cassidy's defeat follows his 2021 vote to impeach President Donald Trump over the Jan. 6, 2021, Capitol riot, leaving him unable to repair the relationship; Trump celebrated the result on social media, declaring his political career "OVER!"
  • Sen. John Kennedy called the downfall "predictable," noting polls showed the moderate in "trouble" before Trump endorsed Letlow, while 66-year-old nurse Jeanelle Chachere described Cassidy as a "phony."
  • During Sunday's "Meet the Press," Sen. Lindsey Graham warned the GOP will punish those who attempt to "destroy" the former president, stating, "If you try to destroy President Trump, you're gonna lose, because this is the party of Donald Trump."
  • The primary result highlights the near-impossibility of maintaining a political future within the Republican Party without Trump's acquiescence, as predictions suggest a similar electoral fate for Kentucky Rep. Thomas Massie if he continues to oppose the MAGA agenda.
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John Kennedy Says Only ‘God’s Perfect Idiot’ Would Have Thought Bill Cassidy Could Survive Primary

'Senator Cassidy was in trouble'

·Houston, United States
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Political Wire broke the news in New York, United States on Sunday, May 17, 2026.
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