Leptin could offer alternative to insulin for managing type 1 diabetes complication

Leptin could offer alternative to insulin for managing type 1 diabetes complication

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

The Brain Can Be Targeted To Treat Type 1 Diabetes – Without Insulin

An analysis published today in The Journal of Clinical Investigation explains how the hormone leptin affects the brain and how it might be used in future therapeutics to treat diabetes. Senior author of the paper, Dr. Michael Schwartz, a UW Medicine endocrinologist, and his team discovered this connection in 2011 when they first administered leptin into the brain of rats with type 1 diabetes. At...

New Insights Into Diabetes Management: Leptin's Role in Combating Diabetic Ketoacidosis

In a groundbreaking analysis published in The Journal of Clinical Investigation, researchers have revealed promising findings about the hormone leptin and its potential to treat diabetic ketoacidosis (DKA), a serious complication associated with type 1 diabetes. This research, spearheaded by Dr. Michael Schwartz from the University of Washington School of Medicine, highlights how leptin can normalize blood sugar levels even in the absence of ins…