Laser-boosted microscopes could reveal new drug targets, sharpen views inside cells

Laser-boosted microscopes could reveal new drug targets, sharpen views inside cells

Link URL: https://www.science.org/content/article/laser-boosted-microscopes-could-reveal-new-drug-targets-sharpen-views-inside-cells Comments URL: https://tildes.net/~science/1v75/laser_boosted_microscopes_could_reveal_new_drug_targets_sharpen_views_inside_cells Votes: 0 Comments: 1

🔬 Most of what's inside the cell is invisible, a new laser method could change that

Today's cryo-electron microscopes can reveal the structure of about 10 percent of human proteins, and less than 1 percent when they sit inside living cells.A new technique from the research institute Biohub and UC Berkeley sharply improves image contrast using a laser 100 million times brighter than the surface of the Sun.Researchers estimate the technology could make more than 50 percent of the proteins that carry out the cell's functions visib…