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Key Alzheimer's protein actively protects neurons from nuclear damage

Researchers say APP helps neurons clear nuclear debris through lysosomal exocytosis, while reduced or mutant APP leaves cells with more inflammation and death markers.

Summary by News Medical
Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD).
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News Medical broke the news in United States on Wednesday, June 17, 2026.
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